A loxP site was inserted upstream of exon 3 and an FRT-flanked neomycin resistance selection cassette followed by a second loxP site were inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette and left exon 3 floxed. (J:275179)
Basic Information
(C57BL/6 x 129P2/OlaHsd)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count