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The targeting construct is designed to insert an internal ribosome entry site (IRES), followed by an mCherry fluorescent protein and the codon-improved cre recombinase (icre) sequence separated by a viral T2A oligopeptide that mediates ribosomal skipping, into the 3' UTR. An FRT-flanked neomycin resistance (neo) cassette was inserted 3' of the cre sequence. Flp-mediated recombination removed the FRT-flanked neo cassette (J:294175)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
