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The BAC clone (bMQ458o12) contains the Glp1r gene flanked by 6 exons of the Dnahc8 gene at the 5' end and the first two exons of the Umod1 gene at the 3' end. A vector containing an optimized Kozak translation initiation sequence, a beta-globin poly-adenylation signal (BpA), the mApple fluorescent reporter, and an FRT-flanked kanamycin/neomycin resistance cassette is inserted into the start codon of the Glp1r gene within the BAC clone. The FRT-flanked cassettes were removed by transient transfection of a FLP recombinase-expressing plasmid. (J:292440)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
