A loxP site was inserted 5' to exon 2 and a loxP-flanked neomycin selection cassette was inserted 3' to exon 2. Cre-mediated recombination in the germline resulted in the deletion of exon 2. (J:281272)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6(Cg)-Tyrc-2J/J
Targeted
Insertion, Intragenic deletion
--
1
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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