A loxP site and FRT-flanked neomycin resistance gene were inserted upstream of exon 5 and a F3-site flanked puromycin resistance gene and a second loxP site were inserted downstream of exon 6. Flp-mediated recombination removed the selection cassettes leaving exons 5-6 floxed. (J:269067)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count