The cDNA for exons 2-9 and the coding part of exon 10, comprising the entire coding region plus part of the 5' UTR, was placed downstream of a tetracycline response element (TRE) and minimal CMV promoter, followed by beta-globin intron and poly signal sequences. Expression of this transgene can be controlled by tetracycline/doxycycline in conjunction with a tTA or rtTA expressing allele. The transgene construct was injected into blastocysts homozygous for the Phenotypes

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6N-Btnl1tm1(KOMP)Mbp
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Insertion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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