A 4 bp deletion was created in the KRAB-A domain using gRNAs and cRNA with CRISPR/Cas9 technology. The resulting truncated peptide, if produced, would lack KRAB domains and zinc fingers. (J:284126)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count