CRISPR/Cas9 genome editing using a single guide RNA (ACAGGCAAGAGGACAAGTCC) is designed to introduce a T-to-C point mutation upstream of the gene locus. (J:101977)
Basic Information
B6.Cg-Apoetm1.1(APOE*4)Adiuj Appem1Adiuj Trem2em1Adiuj/J
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count