The targeting vector contains an FRT-flanked neomycin cassette followed by a loxP site inserted upstream of exon 3 and a second loxP site inserted downstream of exon 3. Flp-mediated recombination removed the FRT-flanked neo cassette leaving exon 3 floxed. (J:290119)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count