The targeting vector is designed to insert a loxP flanked neomycin resistance (neo) cassette, followed by an enhanced green fluorescent protein (EGFP) sequence, directly after the C-terminus of the the gene. Cre-mediated recombination removed the upstream floxed neo cassette. (J:302425)
Basic Information
(C57BL/6 x 129S4/SvJae)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count