A loxP site and an FRT site flanked neomycin resistance gene cassette were inserted into intron 1, and a second loxP site into intron 2. The neo cassette was removed through subsequent flp-mediated recombination, leaving a consitional-ready allele with exon 2 floxed. (J:288818)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count