A cassette incorporating FRT1-loxP1-FRT2-neomycin-FRT1-loxP2 and a copy of Exon3 carrying a 3xStop and mVenus-loxP2-FRT2 was introduced to intron 2, and a loxP1 site was placed in intron 3. The neomycin-FRT1-loxP2-Exon3*(Stop)-IRES-mVenus-loxP2 is skipped and non-functional, without Stop or fluorescent properties. (J:267659)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6 x 129S6/SvEvTac)F1
Targeted
Insertion
--
1
5
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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