A FRT-flanked neomycin cassette and loxP site were introduced to intron 1, a Myc tag was inserted after the signal peptide in exon 2, and loxP and FRT sites were placed in intron 2 of the gene. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:101977)
Basic Information
(C57BL/6J x 129S6/SvEvTac)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count