Log In|Sign Up
EN
CRISPR/Cas9 technology generated a 908 bp deletion that eliminated exon 44, producing a premature stop codon in exon 45. This is one of the most common deletions responsible for Duchenne muscular dystrophy in humans. RT-PCR and product sequencing confirmed the deletion of exon 44. Western blot analysis confirmed the absence of protein. (J:285447)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
