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A BAC containing the mouse Grn gene was engineered about 30 kb DNA region encompassing the Grn promoter and exons 1-13, but not the neighboring Rundc3a, Slc25a39, and Itga2b genes. Line 42 has the lowest expression level of the BAC transgene in the brain (2 fold at mRNA level). (J:147112)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
