The targeting construct inserted between the 5' UTR and coding region a loxP site, a histone fused GFP (H2B-GFP) with a polyadenylation sequence, a loxP site, FRT-flanked neomycin resistance cassette and a triple FLAG epitope tag. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed the GFP reporter. (J:268273)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count