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The transgenic construct contains a loxP-flanked lacZ-neomycin-polyA followed by a human CXCL8 (chemokine (C-X-C motif) ligand 8, also known as IL8) under the control of a CMV-enhanced chicken beta actin promoter (CAG). Founder line 1 has the highest CXCL8 (IL8) expression. (J:288179)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
