The targeting construct inserted a CAG promoter cassette, loxP-flanked transcription termination cassette (STOP) containing a combination of polyadenylation signal, the Nod2 open reading frame together with a Kozak sequence (GCCACC), the human growth hormone polyadenylation signal, and an additional polyadenylation signal. (J:147112)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count