The transgene consists of the chicken beta-actin promoter/CMV enhancer (CAG), loxP flanked STOP cassette, Flag-tagged mouse Ccdc3 coding sequence, IRES2, EGFP sequence and rabbit beta-globin polyA tail. Expression of Ccdc3 is only achieved with cre-mediated excision of the stop cassette. Three lines were generated. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:256481)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count