A 4.5-kb 5' flanking promoter region of the human IL-1beta drives expression of firefly luciferase cDNA. A chicken HS4 insulator (cHS4I) sequence was cloned upstream of the promoter to shield any effect of the chromosomal insertion site on transgene expression. (J:288206)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count