This locus consists of three exons and its expression leads to two transcripts that are testis-specific long noncoding RNAs (lncRNAs). CRISPR/Cas9 genome editing technology was used to delete the entire transcribed region. RT-PCR and qRT-PCR analyses confirmed the absence of expression at the RNA level in the testes of homozygous mutant males. (J:238766, J:288171)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J
Endonuclease-mediated
Intragenic deletion
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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