A loxP site and a Frt-flanked PgkNeopolyA cassette were inserted into the second intron of the gene, and a second loxP site was inserted into the third intron. The neomycin selection cassette was removed via FLP-mediated recombination in the germline. (J:244892)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count