LoxP sites and an frt-flanked neomycin selection casssette were inserted to flank exons 3 and 4. The neomycin selection cassette was removed via FLP-mediated recombination in the germline. (J:243606)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count