LoxP sites were inserted into non-conserved intronic regions 553bp upstream and 530bp downstream of exon 2. The 3' LoxP site was preceded by a Frt-flanked neomycin (Neo) cassette. Exon 2 and the neomycin selection cassette were removed in the germline via FLP and Cre-mediated recombination. (J:287691)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Intragenic deletion
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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