To generate mice with multi-megabase deletion of the Slx ampliconic region, loxP sites were sequentially integrated upstream and downstream of the Slx ampliconic region via CRISPR. Cre-mediated recombination duplicated the floxed region. (J:304511)
Basic Information
(C57BL/6NHsd x DBA/2NHsd)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count