An IRES-Cre-bpA DNA sequence and an frt-flanked neomycin selection cassette was inserted between the stop codon ad the 3'UTR in the third exon. The neomycin selection cassette was subsequently removed via FLP-mediated recombination in the germline. (J:251799)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count