The targeting vector contains (from 5' to 3') a ubiquitously expressed CMV-IE enhancer/chicken beta-actin/rabbit beta-globin hybrid promoter (from pCAGGS), a single FRT site, loxP-flanked stop cassette (containing 3x SV40 polyadenylation [pA] sites), a red fluorescent protein (mCherry) tagged human ATPase, Ca++ transporting, plasma membrane 2 (ATP2B2) splice variant w/b sequence, an SV40pA site followed by a woodchuck hepatitis virus posttranscriptional regulatory element (WPRE), and a neomycin resistance (neo) cassette followed by another SV40pA site. (J:316361)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6N
Targeted
Insertion
--
--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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