A 9.6-kb fragment containing the second coding exon of Rere was retrieved into a pBluescript-derived plasmid containing 500-bp homology arms from BAC clone bMQ386d15 selected from the M37- 129AB22 BAC library. A neomycin resistance cassette flanked by two loxP sites was then inserted 5' to the second coding exon of Rere. A neomycin resistance cassette flanked by an frt site, and an frt and loxP site marked with a BglII restriction site was then inserted 3' to the second coding exon to generate the final targeting vector. (J:94077)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S7/SvEvBrd-Hprt1b-m2
Targeted
Insertion
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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