A 9.6-kb fragment containing the second coding exon of Rere was retrieved into a pBluescript-derived plasmid containing 500-bp homology arms from BAC clone bMQ386d15 selected from the M37- 129AB22 BAC library. A neomycin resistance cassette flanked by two loxP sites was then inserted 5' to the second coding exon of Rere. A neomycin resistance cassette flanked by an frt site, and an frt and loxP site marked with a BglII restriction site was then inserted 3' to the second coding exon to generate the final targeting vector. (J:94077)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count