A loxP site followed by an frt-flanked neomycin resistance gene was inserted upstream of the single coding exon. A second loxP site was inserted downstream of this exon. Flp-mediated recombination removed the neo gene leaving the single exon floxed. (J:303998)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count