A single loxP site was inserted into intron 1, and a Neo cassette with a loxp site was inserted between exon 6 and exon 7. The neo cassette and exons 1-7 were removed via flp and cre-mediated recombination. (J:214946)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count