The sequence encoding the cre/ERT2 fusion protein was inserted in place of the stop codon. A 2A peptide separates the two proteins during translation. Flp-mediated recombination removed the neomycin selection cassette. (J:82809, J:304813)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count