Exon 1 and the exon1-intron 1 boundary were targeted with sgRNAs (targeting TATGGGAACTTTGCTGTCGGTGG and GACCTGGACATTCGGTGAGGAGG) using CRISPR/Cas9 technology, resulting in a 227 bp deletion encompassing the 3' part of the CDS in exon 1. (J:82809)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6N
Endonuclease-mediated
Intragenic deletion
--
1
--
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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