Intron 19 and exon 21 were targeted with sgRNAs (targeting TATGGGTCATGAATAAGGCCTGG and TGTACATCCAGGGTGAGCGGCGG) using CRISPR/Cas9 technology, resulting in a 222bp deletion encompassing exon 20 and a 5' part of exon 21. (J:82809, J:282407)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count