A FLAG-tagged mouse Ace2 gene, preceded by a loxP-flanked Neomycin-translational STOP cassette, was inserted into the endogenous Gt(ROSA)26Sor locus. The loxP flanked STOP cassette was removed via cre-mediated recombination. Ace2 is expressed at high levels in most tissues of the body. (J:286357)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count