A FLAG-tagged mouse Ace2 gene, preceded by a loxP-flanked Neomycin-translational STOP cassette, was inserted into the endogenous Gt(ROSA)26Sor locus. Ace2 is not expressed until the loxP-flanked stop sequence is deleted by Cre-mediated recombination. (J:286357)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count