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Cre-recombination in ES cells containing Cyp2ctm1Wolf inserted the human sequence corresponding to human CYP2C9 exons 1 through 4, intron 4, and exons 5 through 9 linked to a fusion of the 8.5-10.4 kb BamHI/NheI enhancer and 0.3 kb promoter fragment of the mouse albumin upstream regulatory region. Flp-mediated recombination removed the selection cassette. (J:241121)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
