A cassette containing (5' to 3') a lox71 site, FRT site, loxP site, engrailed 2 splice acceptor, betal gal, neo resistance gene, polyadenylation sequence, and a second FRT site. An additional loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the FRT-flanked neo cassette leaving leaving only exon 2 flanked by an upstream lox71 site and a downstream loxP site. (J:172834)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count