CRISPR/Cas9 technology generated a 1.5-kb deletion spanning the locus. RT-PCR and Western blot analysis confirmed the absence of mRNA and protein in the testis and ovaries. Expression of the flanking genes Nudt10 and Nudt11 are unaffected. (J:281161)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count