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Exons 15-23 were replaced with a neomycin selection cassette. Western blot analysis revealed the absence of protein expression in liver lysates, uteri and ovaries from homozygous mice. Immunohistochemical analysis confirmed the absence of protein in kidney epithelial cells, ovary, oviduct and uterus from homozygous mice. (J:286338)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
