Exon 3 was targeted using two gRNAs (AGACCACATGACTCGGAAGAGGG and AGCCACGGAAGGCGGGAATCAGG) and CRISPR/Cas9 technology, resulting in a 182 bp deletion. This causes a frameshift and premature stop codon. (J:285681)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count