CRISPR/Cas9-targeting in Ahrtm3.1Bra zygotes deleted three nucleotides that spans two amino acids resulting in the glycine at 367 and asparigine at 368 being condensed into an arginine at 367.

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.129(FVB)-Ahrtm3.1Bra/Bra
Endonuclease-mediated
Intragenic deletion
--
1
2
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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