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The transgene was made using BAC RP23-353N18 with the improves cre recombinase gene inserted downstream of the Hdnr beta isoform transcriptional start site. The transgene was inserted into a ROSA26R-lacZ reporter harboring mouse embryonic stem cell lines (mESCs). From these mESCs, embryos were generated by tetraploid morula aggregation and analyzed in three embryos derived. (J:284123)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
