Exons 14-16 were flanked by loxP sites. In addition, an EGFP and neomycin selection cassette separated by a loxP site and flanked by FRT sites was inserted upstream of the floxed exons 14-16. Flp-mediated recombination removed the FRT-flanked EGFP and neomycin selection cassette, leaving an FRT site and floxed exons 14-16. (J:276323)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count