This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GTACAGCAGTTATAGCCCGA and AATGGCTCACGGTTAGCAGT, which resulted in a 299 bp deletion beginning at Chromosome 17 position 25,201,004 bp and ending after 25,201,302 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001293958 (exon 4) and 165 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 155 and early truncation 1 amino acids later. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count