Log In|Sign Up
EN
A gene trap cassette containing an FRT site, attB site, Puromycin resistance gene, attP site, human growth hormone poly(A) signal sequence, and FRT site was inserted between exon 1 and exon 2. In addition, exon 2 was flanked by loxP sites. The Puromycin resistance gene was removed via PhiC31-mediated recombination. The human growth hormone poly(A) signal sequence was removed via Flp-mediated recombination. Cre-mediated recombination deleted exon 2. Deletion of exon 2 leads to a frameshift and premature stop codon in exon 3. (J:284914)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
