A loxP-Stop-loxP-Human RHOA cDNA cassette, modified with a Y42C amino acid mutation (nucleotides TAT to TGT) in RHOA, was introduced to an intergenic region downstream of the mouse Col1a1 gene via Flp recombinase-mediated homologous recombination. (J:284071)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6 and 129
Targeted
Nucleotide substitutions
--
1
24
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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