This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AGAGGACATCCTGGGTGTGC and TTGGGCTGCTTTGTCACAAC, which resulted in a 1520 bp deletion beginning at Chromosome 16 position 31,944,262 bp and ending after 31,945,781 bp (GRCm38/mm10). This mutation deletes 1520 bp from ENSMUSE00000387814 (exon 3) and is predicted to cause a change of amino acid sequence after residue 40 and early truncation 45 amino acids later. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count