A loxP site was inserted upstream of exon 17. The targeting vector also inserted downstream of the endogenous exon 17 a neomycin resistance cassette, loxP site and modified exon 17 with an inframe AcGFP reporter gene downstream of the coding sequence with the untranslated sequence preserved. (J:285231)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count