A FRT-loxP-neo-FRT-LoxP cassette was inserted upstream exon 2 and a single loxP site was inserted between exon 5 and 6. The frt-flanked neomycin cassette was removed by FLP-mediated recombination, leaving the loxP sites. (J:284998)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count