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Exons 2-6 of the gene were flanked by loxP sites and a cassette consisting of an adenoviral splice acceptor site fused to an IRES and a GFP gene ws inserted downstream of the second loxP site. An frt-flanked neomycin selection cassette was removed via FLP-mediated recombination. Upon cre-mediated recombination, exons 2-6 are removed and the GFP reporter gene is expressed under the endogenous promoter. (J:262898)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
